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In Israel, Infections Drop Sharply After One Shot of Vaccine

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JERUSALEM — Israel, which leads the world in vaccinating its inhabitants in opposition to the coronavirus, has produced some encouraging information: Early outcomes present a big drop in an infection after only one shot of a two-dose vaccine, and higher than anticipated outcomes after each doses.

Public well being specialists warning that the information, primarily based on the Pfizer-BioNTech vaccine, is preliminary and has not been subjected to medical trials. Even so, Dr. Anat Ekka Zohar, vice chairman of Maccabi Well being Companies, one of many Israeli well being upkeep organizations that launched the information, referred to as it “very encouraging.”

Within the first early report, Clalit, Israel’s largest well being fund, in contrast 200,000 individuals aged 60 or over who obtained a primary dose of the vaccine to a matched group of 200,000 who had not been vaccinated but. It mentioned that 14 to 18 days after their pictures, the partially vaccinated sufferers have been 33 percent less likely to be infected.

At about the identical time, Maccabi’s analysis arm mentioned it had discovered an excellent bigger drop in infections after only one dose: a decrease of about 60 percent, 13 to 21 days after the primary shot, within the first 430,000 individuals to obtain it.

Maccabi didn’t specify an age group or whether or not it had in contrast the information with a matched, non-vaccinated cohort.

On Monday, the Israeli Well being Ministry and Maccabi launched new information on individuals who had obtained each doses of the vaccine, exhibiting extraordinarily excessive charges of effectiveness.

The ministry discovered that out of 428,000 Israelis who had obtained their second doses, per week later solely 63, or 0.014 p.c, had contracted the virus. Equally, the Maccabi information confirmed that greater than per week after having obtained the second dose, solely 20 out of roughly 128,600 individuals, about 0.01 p.c, had contracted the virus.

In medical trials the Pfizer vaccine proved 95 p.c efficient after two doses in stopping coronavirus an infection in individuals with out proof of earlier an infection. The Israeli outcomes, in the event that they maintain up, recommend the efficacy may very well be even increased, although rigorous comparisons to unvaccinated individuals haven’t but been printed.

“That is very encouraging information,” Dr. Zohar mentioned. “We’ll monitor these sufferers carefully with a purpose to look at in the event that they proceed to undergo from delicate signs solely and don’t develop issues on account of the virus.”

Each Clalit and Maccabi warned that their findings have been preliminary and mentioned they’d quickly be adopted by extra in-depth statistical evaluation in peer-reviewed scientific publications.

Israel, the place greater than 40 p.c of the inhabitants has already obtained a primary dose of the vaccine, has turn into one thing of a world check case for vaccination efficacy.

With its small inhabitants, extremely digitized common well being system, and speedy, military-assisted vaccine rollout, Israel’s real-world information gives a helpful complement to medical trials for researchers, pharmaceutical corporations and policymakers.

Israel made a deal with Pfizer through which the drug firm ensured the nation an early and regular provide of vaccines in change for information. The Well being Ministry has made public a redacted version of the settlement.

Regardless of its race to vaccinate, Israel is struggling a devastating third wave of the coronavirus. The federal government reimposed a strict national lockdown this month after weeks of hovering infections and deaths.

Israel was set to halt most air travel in and in a foreign country beginning at midnight on Monday in an effort to dam the arrival of rising virus variants that would threaten the nation’s vaccination marketing campaign. Two vaccine makers mentioned Monday that their vaccines were slightly less effective in opposition to one of many new variants.

Whereas real-world information like that from Israel is beneficial, it’s topic to variables that may skew the outcomes and which medical trials attempt to account for.

Covid-19 Vaccines ›

Solutions to Your Vaccine Questions

Whereas the precise order of vaccine recipients might fluctuate by state, most will doubtless put medical employees and residents of long-term care services first. If you wish to perceive how this resolution is getting made, this article will help.

Life will return to regular solely when society as an entire positive factors sufficient safety in opposition to the coronavirus. As soon as international locations authorize a vaccine, they’ll solely be capable of vaccinate a number of p.c of their residents at most within the first couple months. The unvaccinated majority will nonetheless stay susceptible to getting contaminated. A rising variety of coronavirus vaccines are exhibiting strong safety in opposition to turning into sick. But it surely’s additionally potential for individuals to unfold the virus with out even realizing they’re contaminated as a result of they expertise solely delicate signs or none in any respect. Scientists don’t but know if the vaccines additionally block the transmission of the coronavirus. So in the interim, even vaccinated individuals might want to put on masks, keep away from indoor crowds, and so forth. As soon as sufficient individuals get vaccinated, it would turn into very tough for the coronavirus to search out susceptible individuals to contaminate. Relying on how rapidly we as a society obtain that purpose, life would possibly begin approaching one thing like regular by the autumn 2021.

Sure, however not without end. The 2 vaccines that can doubtlessly get approved this month clearly shield individuals from getting sick with Covid-19. However the medical trials that delivered these outcomes weren’t designed to find out whether or not vaccinated individuals might nonetheless unfold the coronavirus with out growing signs. That continues to be a chance. We all know that people who find themselves naturally contaminated by the coronavirus can unfold it whereas they’re not experiencing any cough or different signs. Researchers might be intensely learning this query because the vaccines roll out. Within the meantime, even vaccinated individuals might want to consider themselves as potential spreaders.

The Pfizer and BioNTech vaccine is delivered as a shot within the arm, like different typical vaccines. The injection received’t be any totally different from ones you’ve gotten earlier than. Tens of 1000’s of individuals have already obtained the vaccines, and none of them have reported any severe well being issues. However a few of them have felt short-lived discomfort, together with aches and flu-like signs that sometimes final a day. It’s potential that individuals might must plan to take a break day work or faculty after the second shot. Whereas these experiences aren’t nice, they’re a superb signal: they’re the results of your personal immune system encountering the vaccine and mounting a potent response that can present long-lasting immunity.

No. The vaccines from Moderna and Pfizer use a genetic molecule to prime the immune system. That molecule, referred to as mRNA, is finally destroyed by the physique. The mRNA is packaged in an oily bubble that may fuse to a cell, permitting the molecule to slide in. The cell makes use of the mRNA to make proteins from the coronavirus, which might stimulate the immune system. At any second, every of our cells might comprise a whole bunch of 1000’s of mRNA molecules, which they produce with a purpose to make proteins of their very own. As soon as these proteins are made, our cells then shred the mRNA with particular enzymes. The mRNA molecules our cells make can solely survive a matter of minutes. The mRNA in vaccines is engineered to resist the cell’s enzymes a bit longer, in order that the cells could make further virus proteins and immediate a stronger immune response. However the mRNA can solely final for a number of days at most earlier than they’re destroyed.

The early Israeli numbers are primarily based on the primary individuals to get the vaccine. Such individuals, specialists say, are more likely to be extra involved or knowledgeable in regards to the virus and due to this fact extra cautious about social distancing and masks carrying. They may additionally differ from those that didn’t rush to get the shot by location and socio-economic standing.

Additionally, specialists say, the illness adjustments over time. Prof. Ran Balicer, the chief innovation officer at Clalit and a number one Israeli epidemiologist, mentioned that two-week-old information may be like proof from a special period or “about 1,000,000 vaccines in the past in Israeli phrases.”

Maccabi mentioned that it will launch extra information weekly. “The primary message,” Maccabi mentioned in a press release, is that even the primary dose of the vaccine “is efficient and reduces morbidity and lowers hospitalizations by many tens of p.c.”

A hazard of releasing uncooked information, specialists cautioned, is that it may be misinterpreted.

After Clalit first publicized its early numbers two weeks in the past, many individuals heard a couple of 33 p.c drop in circumstances, not the anticipated 95 p.c, and jumped to the misguided conclusion that the Pfizer shot didn’t work.

There was an uproar in Britain, the place the authorities have delayed giving the second dose by as much as 12 weeks, versus the 21-day hole on which Pfizer primarily based its trials.

Professor Balicer considered the outcomes as excellent news and was dismayed at how they have been interpreted.

“We have been reassured sufficient to inform everybody that we have been seeing what we have been alleged to be seeing proper after Day 14,” he mentioned. “I don’t know the way it become a message of ‘Oh my God, it doesn’t work.’”

Professor Balicer, who can also be the chairman of the group of specialists advising the Israeli authorities on its Covid-19 response, hoped the constructive outcomes may need a bearing on an imminent authorities resolution relating to a 3rd lockdown.

“Covid has turned us all into newbie scientists,” mentioned Talya Miron-Shatz, an affiliate professor and skilled in medical decision-making at Ono Educational Faculty in central Israel. “We’re all taking a look at information, however most individuals are usually not scientists.”

Israel, which started vaccinating individuals on Dec. 20, has given a primary shot to greater than 2.6 million Israelis and each pictures to greater than 1,000,000 individuals.

After beginning with individuals aged 60 and above, well being care employees and others at excessive danger, Israel is now providing vaccines to individuals over 40 and to highschool college students aged 16 to 18 to permit them to get again to highschool. The army is helping the hassle and 700 military reserve medics are serving to at vaccination facilities.

Prof. Jonathan Halevy, the president of Shaare Zedek Medical Middle in Jerusalem, had not studied the findings of the H.M.O.s however mentioned that two weeks after the primary dose was rolled out he started seeing a drop in extreme circumstances.

“I do know a number of individuals who turned contaminated near the time they acquired the vaccine, however they acquired it frivolously,” he mentioned.

Nonetheless, Israel stays underneath a nationwide lockdown and officers are involved in regards to the emergence of latest, extremely contagious variants. It stays to be seen how effective the vaccines are against the new variants.

Regardless of what seems to be the early success of the vaccine, the virus continues to wreak havoc in Israel. Professor Halevy mentioned his hospital’s Covid wards have been nonetheless packed to capability and he anticipated that it will take one other two or three weeks to see a decline.

The virus has killed greater than 1,000 Israelis to this point this month alone, almost 1 / 4 of those that have died from the pandemic virus general.

Well being officers and specialists have attributed a lot of the current enhance in an infection to the fast-spreading variant first detected in Britain.

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Biden Officials Now Expect Vulnerable Americans to Need Booster Shots

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WASHINGTON — Biden administration health officials increasingly think that vulnerable populations will need booster shots even as research continues into how long the coronavirus vaccines remain effective.

Senior officials now say they expect that people who are 65 and older or who have compromised immune systems will most likely need a third shot from Pfizer-BioNTech or Moderna, two vaccines based on the same technology that have been used to inoculate the vast majority of Americans thus far. That is a sharp shift from just a few weeks ago, when the administration said it thought there was not enough evidence to back boosters yet.

On Thursday, a key official at the Centers for Disease Control and Prevention said the agency is exploring options to give patients with compromised immune systems third doses even before regulators broaden the emergency use authorization for coronavirus vaccines, a step that could come soon for the Pfizer vaccine.

Dr. Amanda Cohn, the chief medical officer of the C.D.C.’s immunizations division, told an advisory committee to the agency that officials were “actively looking into ways” to provide certain people access to booster shots “earlier than any potential change in regulatory decisions.”

“So stay tuned,” she added.

The growing consensus within the administration that at least some Americans will need a booster is tied in part to research suggesting that the Pfizer vaccine is less effective against the coronavirus after about six months. More than half of those fully vaccinated in the United States so far have received Pfizer’s vaccine, in two doses administered three weeks apart.

Pfizer’s continuing global study of its clinical trial participants shows that four to six months after the second dose, the vaccine’s effectiveness against symptomatic infection drops from a high of 95 percent to 84 percent, according to the company.

Data from the Israeli government, which has fully vaccinated more than half of its population with Pfizer doses since January, also points to a downward trend in effectiveness over time, although administration officials are viewing that data cautiously because of wide margins for error.

The most recent figures from the Israeli Ministry of Health, released late this week, suggested that Pfizer’s vaccine was just 39 percent effective in preventing infection in that country in late June and early July, compared to 95 percent from January to April.

The vaccine remained more than 90 percent effective in preventing severe disease, and nearly as effective in preventing hospitalization. Israel began offering a third Pfizer dose to citizens with severely weakened immune systems on July 12.

Dr. Anthony S. Fauci, who heads the infectious disease division of the National Institutes of Health, said he was surprised by the apparent steep falloff in the Pfizer vaccine’s effectiveness that the Israeli data seems to suggest. He said he wanted to compare it with data that the C.D.C. had been gathering from cohorts of thousands of people across the United States. “People are sort of raising their eyebrows a bit,” he said.

While other questions abound, senior administration officials said it appeared increasingly clear that the vaccines would not grant indefinite immunity against the virus, and that boosters might be necessary for at least some people perhaps nine months after their first shot. The administration has already purchased more than enough vaccine to deliver third doses of both Pfizer and Moderna, and has been quietly preparing to expand the distribution effort, should it become necessary.

With so little data yet public, many health officials and experts have spoken cautiously about booster shots. Dr. Paul A. Offit, a member of the Food and Drug Administration’s outside advisory committee of vaccine experts, said a rise in mild or moderate cases of Covid-19 among vaccinated people did not necessarily mean a booster was required.

“The goal of this vaccine is not to prevent mild or low, moderate infectious disease,” he said. “The goal is to prevent hospitalization to death. Right now this vaccine has held up to that.”

Prematurely dangling the prospect of a third dose could also work as a deterrent against vaccination, other health experts warn. If Americans think that immunity from the vaccines is short-lived, they said, they may be less likely to get their initial shot.

“We don’t want people to believe that when you’re talking about boosters, that means that the vaccines are not effective,” Dr. Fauci testified at a congressional hearing Tuesday. “They are highly effective.”

Among the vaccine manufacturers, Pfizer has been especially proactive in sharing its data with the government. But the administration was taken aback by the company’s public announcement this month that it planned to seek emergency authorization from the F.D.A. for a booster shot.

The company said that early data from its booster study showed the level of neutralizing antibodies among clinical trial participants who received a third dose six months after the second was five to 10 times as high as among two-dose recipients.

Fearful the American public would get the wrong message, the F.D.A. and the C.D.C. reacted with an unusual public statement saying, “Americans who have been fully vaccinated do not need a booster shot at this time.” They added, “We are prepared for booster doses if and when the science demonstrates that they are needed.”

Typically, the F.D.A. would authorize use of a booster, perhaps after a meeting of its outside advisory committee. Then the C.D.C., which has its own advisory committee, would need to formally recommend it, Dr. Offit said.

But if the F.D.A. fully licenses a vaccine, doctors would have vastly more leeway to prescribe a booster for their patients. Some health experts expect that Pfizer could receive that approval by this fall.

At the C.D.C. advisory panel’s meeting Thursday, Dr. Cohn, the medical officer for the vaccine division, suggested that it might be possible to offer booster shots to those with weakened immune systems through an investigational study or other avenues, without waiting for the F.D.A.

Dr. Camille Kotton, an infectious disease expert with Massachusetts General Hospital, told the panel that some patients, especially those who are more educated or “empowered to take care of their own health care,” are managing to get a third dose on their own, despite the lack of a green light from the government.

“Many have taken matters into their own hands,” she said. “I am concerned about them doing this kind of in an unsupervised fashion,” she said, while doctors’ hands are tied because of the lack of regulatory approval.

People with compromised immune systems make up 2.7 percent of the population, according to the C.D.C., and include those with cancer, organ or stem cell transplants or H.I.V., among other conditions.

At Tuesday’s hearing of the Senate’s health committee, several senators grilled administration health officials on how soon they would act on the question of boosters. Senator Mitt Romney, a Utah Republican, said he was unhappy that officials could not provide a better timetable.

Senator Richard M. Burr, a North Carolina Republican, noted that Israel was already offering some of its most vulnerable citizens a third shot. “Why aren’t we making the same decisions?” he asked.

Dr. Rochelle Walensky, the director of the C.D.C., testified that scientists were studying the vaccines’ efficacy in tens of thousands of people, including nursing home residents and more than 5,000 essential workers.

“Fortunately, we’re anticipating that this will wane and not plummet,” she said of their efficacy. “As we see that waning, we — that will be our time for action.”

Pfizer is expected to soon publicize its clinical trial research about waning immunity and the benefits of a booster shoot in articles in a peer-reviewed journal. Moderna has yet to release data on any booster studies, officials said.

Johnson & Johnson’s one-shot vaccine has so far played a minor role in the nation’s vaccination campaign. Clinical trial data on how that vaccine works with two shots is expected next month.

Noah Weiland contributed reporting.

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Hole Blasted In Guntrader: UK Firearms Sales Website’s CRM Database Breached, 111K Users’ Info Spilled Online

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Criminals have hacked into a Gumtree-style website used for buying and selling firearms, making off with a 111,000-entry database containing partial information from a CRM product used by gun shops across the UK. The Register reports: The Guntrader breach earlier this week saw the theft of a SQL database powering both the Guntrader.uk buy-and-sell website and its electronic gun shop register product, comprising about 111,000 users and dating between 2016 and 17 July this year. The database contains names, mobile phone numbers, email addresses, user geolocation data, and more including bcrypt-hashed passwords. It is a severe breach of privacy not only for Guntrader but for its users: members of the UK’s licensed firearms community. Guntrader spokesman Simon Baseley told The Register that Guntrader.uk had emailed all the users affected by the breach on July 21 and issued a further update yesterday.

Guntrader is roughly similar to Gumtree: users post ads along with their contact details on the website so potential purchasers can get in touch. Gun shops (known in the UK as “registered firearms dealers” or RFDs) can also use Guntrader’s integrated gun register product, which is advertised as offering “end-to-end encryption” and “daily backups”, making it (so Guntrader claims) “the most safe and secure gun register system on today’s market.” [British firearms laws say every transfer of a firearm (sale, drop-off for repair, gift, loan, and so on) must be recorded, with the vast majority of these also being mandatory to report to the police when they happen…]

The categories of data in the stolen database are: Latitude and longitude data; First name and last name; Police force that issued an RFD’s certificate; Phone numbers; Fax numbers; bcrypt-hashed passwords; Postcode; Postal addresses; and User’s IP addresses. Logs of payments were also included, with Coalfire’s Barratt explaining that while no credit card numbers were included, something that looks like a SHA-256 hashed string was included in the payment data tables. Other payment information was limited to prices for rifles and shotguns advertised through the site. The Register recommends you check if your data is included in the hack by visiting Have I Been Pwned. If you are affected and you used the same password on Guntrader that you used on other websites, you should change it as soon as possible.

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Protest erupts at Myanmar’s Insein prison amid COVID outbreak | Military News

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A protest has erupted at a prison in Myanmar’s commercial capital of Yangon against what activists said was a worsening COVID-19 outbreak at the jail, which is used to hold opponents of February’s military takeover.

The protest on Friday was one of the first of its kind since the February 1 coup in the Southeast Asian country, where people across the country demonstrate daily against military rule.

Protest chants in opposition to the military government could be heard from inside the colonial-era Insein Prison early on Friday in videos recorded from outside the prison and posted by local residents to Facebook.

“End the dictatorship! Our cause! Protest, protest! Start, start! Revolution! Must prevail!” the call-and-response chant went.

The Thailand-based activist group, Assistance Association for Political Prisoners (AAPP) said the protest began in the women’s detention block and had been supported by some prison staff members. Reuters could not immediately verify the report.

“A riot happened in the prison,” Myanmar Prison Department’s Deputy Director Chan Nyein Kyaw told state-run news outlet Myawaddy. “There was a negotiation and accepted the prisoners’ demands and requests.”

AAPP said the military had entered the prison compound earlier on Friday and confiscated staff weapons.

Prison spokesperson Zaw Zaw did not answer phone calls from Reuters seeking comment about the protest and the report that the military had intervened. He told local media the protest had been brought under control. Calls to military spokesperson Zaw Min Tun went unanswered.

‘End standoff’

Diplomats called for an end to the standoff.

“We urge the relevant authorities to resolve the situation peacefully and respect the basic right to proper healthcare for all those detained inside this and other prisons,” a group of diplomatic missions including Australia, Canada, the United Kingdom, the United States and nine European Union member states said in a joint statement posted on Facebook.

Earlier this month, Myanmar freed more than 2,000 detainees from the prison, among them journalists and others who the military said had been held on incitement charges for taking part in protests.

Myanmar’s military has struggled to impose order and a growing COVID-19 outbreak has added to the chaos. Myanmar registered more than 6,000 new COVID-19 infections on Thursday after reporting 286 deaths a day earlier, both record highs.

The protest on Friday was one of the first of its kind since the February 1 coup in the Southeast Asian country, where people across the country demonstrate daily against military rule [File: Ann Wang/Reuters]

Medics and funeral services have said the real death toll is far higher, with crematoriums unable to keep pace, and the military has arrested several doctors treating COVID-19 patients independently.

“The protest reportedly began because prisoners have not been provided with medical care, and neither have prison staff been given protection from COVID-19,” the AAPP statement said.

Nyan Win, a senior adviser to overthrown leader Aung San Suu Kyi, died in hospital on Tuesday after becoming infected with COVID-19 in the prison.

UK ambassador replaced

In a separate development, Myanmar has appointed a new temporary head of its embassy in London, the UK’s foreign ministry said, replacing the previous ambassador who was removed after breaking ranks with the military government over the coup.

The selection of the new “charge d’affaires ad interim” did not require the consent of the British government, a foreign ministry spokesperson told Reuters, which first reported the move earlier on Friday.

More than 900 people opposing the military government have been killed by security forces since the coup, drawing international condemnation and sanctions including from the UK.

“The consent of the receiving State is not required,” the spokesperson said in a statement, citing the Vienna Convention on Diplomatic Relations. The statement did not name the new appointee.

A spokesperson for the military-controlled government in Myanmar did not respond to calls from Reuters seeking comment.

The Myanmar Accountability Project, a UK-based rights group, said the appointee for the London job was Htun Aung Kyaw, who served as a fighter pilot during a long army career.

A source familiar with the matter also said Htun Aung Kyaw was Myanmar’s new pick, but Reuters could not confirm that.

In a statement this week, the Myanmar Accountability Project urged the UK not to recognise the representative appointed by the military saying it would be “a gross double standard and a moral outrage”.

The former ambassador, Kyaw Zwar Minn, was locked out of the London embassy in April after calling for the release of detained civilian leader Aung San Suu Kyi.

Kyaw Zwar Minn remains in the UK and has urged the British government to refuse to recognise any envoys appointed by the military government and to send them back to Myanmar.

The UK has imposed sanctions on members of Myanmar’s military and some of its business interests following the coup, and has called for democracy to be restored.

The UK on Friday appointed a new ambassador to Myanmar, Pete Vowles, who previously worked in diplomatic and international development roles in Africa and Asia.

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NSO Group CEO Says Law-Abiding Citizens Have ‘Nothing To Be Afraid Of’

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The CEO of NSO Group, whose spyware tools have reportedly been used to target journalists and activists, says that people who aren’t criminals shouldn’t be afraid of being surveilled AppleInsider reports: Shalev Hulio, 39, recently spoke to Forbes after investigations indicated that NSO Group’s Pegasus spyware was used by authoritarian governments to hack and surveil the mobile devices of world leaders, high-profile journalists, and activists. NSO Group says that it sells its tools to governments to help them catch serious criminals like terrorists or gangsters. However, Hulio admitted that it can’t control what governments ultimately do with the tools. “We are selling our products to governments. We have no way to monitor what those governments do,” he said.

Hulio did note that NSO Group has mechanisms in place to detect when abuse happens so that the company can “shut them down.” He says that NSO Group has “done it before and will continue to do so. On the other hand, he said that NSO Group shouldn’t be responsible for government misuse. Additionally, Hulio said that the average smartphone has nothing to worry about. While NSO Group’s spyware can break into the latest iPhones running up-to-date software, often without any action from the user, it’s only aimed at criminals. “The people that are not criminals, not the Bin Ladens of the world — there’s nothing to be afraid of. They can absolutely trust on the security and privacy of their Google and Apple devices,” Hulio said.

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The Activision Blizzard Harassment Suit Feels Painfully Familiar

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Gaming behemoth Activision Blizzard is the latest game company to face scrutiny for allegedly fostering a culture of sexism. A California Department of Fair Employment and Housing suit filed Wednesday alleges rampant sexual harassment and discrimination against Activision Blizzard’s female employees. The suit’s spotlight on Activision Blizzard’s structures and systems are painfully similar to those exposed by lawsuits and exposés around Riot Games and Ubisoft from the last several years.

The games industry’s reckoning with workplace inequality has been underway for years. Leading companies have been slow, even reticent, to answer for their reportedly discriminatory cultures, in some cases architecting fortresses of asylum around their more problematic employees and systems. Activision Blizzard has the opportunity to set a different tone. As of now, it seems unlikely to.

The games industry is notoriously male-dominated, and has long had a reputation for hostility to women. The 29-page DFEH complaint follows a two-year investigation into Activision Blizzard—publisher of high-profile titles like Call of Duty, World of Warcraft, and Overwatch—and contains hair-raising allegations of misconduct, from harassment by top executives to so-called “cube crawls,” in which male employees would reportedly “drink copious amounts of alcohol as they ‘crawl’ their way through various cubicles in the office and often engage in inappropriate behavior toward female employees.” It describes a culture in which double standards prevented women from advancing and even remaining at the company; across the board, it says, women receive less pay than men for “substantially similar work.” The agency alleges that female employees receive a lower starting pay than men and are promoted more slowly. Only 24 percent of Activision Blizzard’s nearly 10,000 employees are women, and top leadership is almost entirely white and male.

In this “frat boy” culture, the complaint reads, men “proudly” came to work hungover, delegated responsibilities to women while they played games like Call of Duty, openly discussed sexual encounters, and even joked about rape. The complaint also alleges that employees and even executives sexually harassed female employees without repercussions. It states that a female employee who may have experienced sexual harassment at work—including an instance when coworkers at a party allegedly shared an intimate photo of her—later committed suicide. (In a statement, Activision Blizzard says, “We are sickened by the reprehensible conduct of the DFEH to drag into the complaint the tragic suicide of an employee whose passing has no bearing whatsoever on this case and with no regard for her grieving family.”)

“We value diversity and strive to foster a workplace that offers inclusivity for everyone,” an Activision Blizzard spokesperson said in a statement. “There is no place in our company or industry, or any industry, for sexual misconduct or harassment of any kind. We take every allegation seriously and investigate all claims. In cases related to misconduct, action was taken to address the issue.” The company says it has made an effort over the last several years to bolster diversity, including helping employees report violations, adding a confidential hotline, and instituting a team to investigate workers’ concerns. Activision Blizzard claims that the DFEH complaint includes “distorted, and in many cases false, descriptions of Blizzard’s past.”

The DFEH is asking for relief for compensatory and punitive damages, unpaid wages, and attorneys fees. Citing the ongoing investigation, the department declined to respond to WIRED’s request for comment.

The Activision Blizzard revelations echo those around Riot Games in 2018 and Ubisoft in 2020. Just as gaming culture at large has been slow to embrace women and minorities, gaming companies previously accused of fostering cultures of sexism have been slow to evolve.

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